Inombolo ye-Florfenicol Cas: 73231-34-2 Ifomula yeMolekyuli: C12H14Cl2FNO4S

Inkcazelo emfutshane:

Inombolo yeCas: 73231-34-2

Igama leKhemikhali: Florfenicol

Ifomula yeemolekyuli:C12H14Cl2FNO4S

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Izithethantonye

2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
AQUAFEN FLORFENICOL NUFLOR
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r-(r*,s*))-methyleste
2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzenesulfonicaci
Florfeniol
FLUPROFEN
I-Fluorothiamphenicol
Sch-25298, Aquafen
IAcetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl ]iacetamide
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid

Inkcazo yeeMveliso

Indawo yokunyibilika	153 °
Ukuxinana	1.451±0.06 g/cm3(Eqikelelweyo)1.1782(uqikelelo olurhabaxa)
ixesha lokugcina	2-8°C
ukunyibilika	Inyibilika kwi-ethanol ukuya kwi-25mM nakwi-DMSO ukuya kwi-100mM
umsebenzi wamehlo	N / A
Imbonakalo	Mhlophe ukuya kuMhlophe
Ubunyulu	≥98%

Inkcazo

I-Flofenicol yi-antibiotic ebanzi ye-fluorinated kunye ne-derivative ye-thiamphenicol (Inqaku le-21357).Iyasebenza ngokuchasene neklinikhi yabantu ababodwa kwiintsholongwane ze-enteric, kuquka i-E. coli, i-Klebsiella, i-Enterobacter, i-Citrobacter, i-P. mirabilis, kunye ne-Salmonella (MIC₅₀s = 6.3-12.5 μg / ml).I-Flofenicol iphinda isebenze ngokuchasene neekliniki ezahlukeneyo zezilwanyana zeenkomo kunye ne-porcine ye-respiratory pathogens, kuquka i-P. multocida, i-A. pleuropneumoniae, kunye ne-B. bronchiseptica (MIC₅₀s = 0.25-4 μg / ml).Ivimbela umsebenzi we-peptidyl transferase kwi-70S ribosomes ehlukanisiwe ne-E. coli xa isetyenziswe kwi-concentration ye-1 mM.Iifomyula eziqukethe i-florfenicol zisetyenziswe kunyango lwesifo esosulelayo sokuphefumla kwiinkomo.

ukusetyenziswa kunye nethamo

Luhlobo lwechiza lokulwa ne-antibacterial.Isetyenziswa njengeyeza lezilwanyana lokunyanga izifo zehagu, iinkukhu kunye neentlanzi.Isebenza kakuhle ekunyangeni isifo seehagu, iinkukhu kunye neentlanzi esibangelwa yintsholongwane ebuthathaka, ingakumbi ekunyangeni izifo zokuphefumula kunye nosulelo lwamathumbu.