Inombolo yeCas: 168273-06-1 Ifomula yeMolekyuli:C22H21Cl3N4O

Iimveliso

Inombolo yeCas: 168273-06-1 Ifomula yeMolekyuli:C22H21Cl3N4O

Inkcazelo emfutshane:

Inombolo yeCas: 168273-06-1

Igama leKhemikhali:Phenolphthalein

Ifomula yeemolekyuli:C22H21Cl3N4O

Izithethantonye:5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidino-1H-pyrazole-3-carboxamide


Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo yeeMveliso

Indawo yokunyibilika 154.7 °C
Ukuxinana 1.299
ixesha lokugcina akukho zithintelo.
ukunyibilika I-Soluble kwi-DMSO (ukuya kwi-20 mg / ml) okanye kwi-Ethanol (ukuya kwi-20 mg / ml).idimethyl sulfoxide kwaye ayinyibiliki kwibenzene okanye ihexane.
umsebenzi wamehlo N / A
Imbonakalo mhlophe ukuya kokukhanya kwekristale powde emthubi
Ubunyulu ≥98%

Inkcazo

ngumchasi ochasene ne-cannabinoid receptor (CB1).Isebenza ngokuthintela ngokukhethekileyo i-CB1 i-receptors efunyenwe kwingqondo nakwizitho ezithintekayo ezibalulekileyo kwi-glucose kunye ne-lipid metabolism, kuquka izicubu ze-adipose, isibindi, i-gastrointestinal tract, kunye nemisipha.Ke, ibandakanya indlela yonyango yokutyeba kakhulu kunye nezinto ezinobungozi bentliziyo.Njengeziyobisi ezichasene ne-anorectic antiobesity, yayisetyenziswe njengenxalenye yokutya kunye nokuzilolonga kwizigulane ezityebileyo okanye ezigqithiseleyo kunye nezinto ezinobungozi ezinxulumene neYurophu kwi-2006. Nangona kunjalo, iziphumo ezibi ezibandakanya ukuzibulala, ukudakumba, kunye nokuxhalaba zaxelwa, ngokusekelwe apho i-rimonadant ihoxisiwe. kwihlabathi liphela ngo-2008.
I-Andogenous cannabinoids inxulumene nesiphumo esithandekayo se-nicotine, njenge-cannabinoid receptor blocker, iphinda ivavanywe njengonyango oluchasene nokutshaya.

sebenzisa

yi-immunomodulatory CB1 receptor inverse agonist

ukusetyenziswa kunye nethamo

Cela uGqirha acebise kuqala

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