Inombolo yeCas: 171599-83-0 Ifomula yeMolekyuli: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70

Inkcazelo emfutshane:

Inombolo yeCas: 171599-83-0
Igama leMchiza:
Ifomula yemolekyuli: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
Ii-synonyms: i-N-methyl-4-ethoxyamphetamine, i-4-ethoxy-N-, i-PMK Methyl Glycidate, i-PMK glycidate, i-PMK methyl glycidate, i-PMK kunye ne-MDP2P, njl.

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

ukucaciswa kweemveliso

Indawo yokunyibilika	49-53 °
Ukuxinana	1.05 g/cm³
ixesha lokugcina	indawo epholileyo, eyomileyo kwaye uthintele ukuchanabeka ekukhanyeni okanye kubushushu obuphezulu
ukunyibilika	Inyibilika ngokulula kwi-ethanol, i-acetone, i-ether, ibenzene kunye ne-methylene chloride, kodwa ayinyibiliki emanzini.
umsebenzi wamehlo	[α]D20 = +61.0 ° (isisombululo se-ethanol)
Imbonakalo	mhlophe ukuya kokukhanya komgubo wekristale otyheli

iimveliso pharmacology

Ngexesha lokuvuselela ngokwesondo, i-nerve parasympathetic, i-non adrenergic kunye ne-noncholinergic nerve (NANC) iziphelo kunye neeseli ze-vascular endothelial zikhupha i-nitric oxide (NO) phantsi kwesenzo se-nitric oxide synthase (NOS).Kwimithanjana yegazi, i-soluble guanylate cyclase (sGC) idla ngokusetyenziswa ngu-NO, kwaye i-sGC isebenza kwi-guanosine triphosphate ukuvelisa i-cGMP.I-cGMP kwi-corpus cavernosum ye-penis yenza impembelelo enamandla ye-vasodilator ngokunciphisa ukuxinwa kwe-Ca2 + kwiiseli ze-muscle ezigudileyo ze-corpus cavernosum, ezibangela ukuphumla kweeseli ze-muscle ezigudileyo kunye nokwanda kokuhamba kwegazi ngaphakathi kwe-corpus cavernosum, ekhokelela. kwi erection.I-alkali ye-Jinyang iyanciphisa iqondo lokuthotywa kwe-cGMP, ngaloo ndlela igcina umphumo wokuphumla we-cGMP kwi-corpus cavernosum ye-penis kunye nokubangela ukumiswa kwepenile.Kwi-vivo, i-cGMP ithotywa kwaye ayisebenzi yi-PDE5.

iimveliso Sebenzisa

Ilungele ukunyanga i-erectile dysfunction (ED) yelungu lobudoda, iyasebenza kwi-erectile dysfunction ebangelwa kusetyenziso lwe-antidepressants, antipsychotics, kunye neziyobisi ezilwa noxinzelelo lwegazi, kunye nokungasebenzi kakuhle kwe-erectile okubangelwa lutyando okanye ukwenzakala.

Ukusetyenziswa kunye nomthamo

Ingenziwa iipilisi, iipilisi, ii-capsules eziqinileyo, ii-capsules ezithambileyo, kwaye zinokusetyenziswa njengeyeza lewayini, ulwelo lomlomo, ikofu, iigranules, iipilisi ezihlafunwayo, iilozenge, itshungama kunye nezinye iifom zedosi.Kubantu abadala, i-dosage kufuneka ibe yi-10-100mg ngosuku, enokwandiswa okanye iyancipha ngokwemeko yomsebenzisi.Kungcono ukuyithatha ngesisu esingenalutho (ngokukodwa kuphephe ukuyithatha ngokutya okunamafutha amaninzi), kwaye ungaseli utywala ngaphambi kokusetyenziswa kweTea (ukuthatha akufanele kusetyenziswe ngexesha elifanayo, oko akuthethi ukuba ukusela utywala ngexesha elifanayo. ixesha linokunciphisa kakhulu umsebenzi we-erectile weViagra).
Ixesha elisebenzayo: Uninzi lwabantu luthatha iyure enye ukuba lusebenze.Kunconywa ukuba uthathe amayeza malunga neyure ye-1 ngaphambi kokulala ngesondo, kunye nemiphumo yayo ehlala kwii-48 kwiiyure ze-72, kwaye ezinye zinokuhlala iiyure ze-116.