Inombolo ye-Orlistat Cas: 132539-06-1 Ifomula yeMolekyuli: C28H29NO
| Indawo yokunyibilika | 195-200°C |
| Ukuxinana | 1.4 g/cm³ |
| ixesha lokugcina | 2-8℃ |
| ukunyibilika | ayinyibiliki emanzini, inyibilika kancinane kwi-ethanol, inyibilika ngokulula kwichloroform kunye nemethanol |
| umsebenzi wamehlo | +71.6 (c=1.0, ethanol) |
| Imbonakalo | umgubo omhlophe okanye omhlophe wekristale |
I-Olistat yinto ehlala ixesha elide, i-gastrointestinal lipase inhibitor enokuthi ithintele i-hydrolysis ye-triglycerides kwi-absorbeble fatty acids kunye ne-monoacylglycerols, ithintele ukuba ifakwe, ngaloo ndlela inciphisa ukuthathwa kwekhalori kunye nokulawula ubunzima.Xa isetyenziswe njengamayeza angaphezulu kwe-counter-counter-counter treatments, i-orlistat ifanelekile kunyango lwezigulane ezigqithiseleyo okanye ezigqithiseleyo (kunye ne-index mass body of ≥ 24 kunye nokubala okuqikelelwayo kobunzima / ubude be-2).
I-Orlistat liyeza lokulahlekelwa kwesisindo, lithengiswa njenge-Xenical.
I-Olistat yimveliso egcweleyo ye-lipstatin.I-Lipstatin yindalo esebenzayo ye-pancrelipase inhibitor ehlukanisiwe ne-Streptomyces toxitricini Isebenza kakhulu kwi-gastrointestinal tract.Iyakwazi ukuvimbela i-enzymes efunekayo kwi-gastrointestinal tract ukugaya amanqatha, kuquka i-pancreatic ester kunye ne-ester ye-gastric, kunye nokunciphisa ukuxutywa kwe-ester ye-gastrointestinal kumafutha okunceda ukunciphisa umzimba, kodwa kusafuneka kudibaniswe nokuzivocavoca kunye nokutya ukuze unciphise umzimba.
Umthamo onconywayo we-Olistat capsules yi-0.12g capsules ezithathwe ngokutya okanye kwiyure enye emva kokutya.Ukuba kukho ukutya okungazange kutyiwe okanye ukuba ukutya akunamafutha, iyeza elinye linokukhutshwa.Umphumo wonyango wokusetyenziswa kwexesha elide le-orlistat capsules, kubandakanywa ukulawula ubunzima kunye nokuphuculwa kwezinto ezinobungozi, kunokugcinwa.Ukutya kwesigulana kufuneka kulinganiswe kwisondlo, kunye nokutya okuphantsi kweekhalori.Ngokumalunga ne-30% yeekhalori ezithathayo zivela kumafutha, kwaye ukutya kufuneka kube zizityebi kwiziqhamo kunye nemifuno.
