Inombolo ye-Phenformin Cas: 834-28-6 Ifomula yeMolekyuli: C10H16N8
Indawo yokunyibilika | 150-155℃ |
Ukuxinana | 1.197g/cm³ |
ixesha lokugcina | 2-8℃ |
ukunyibilika | Inonyibiliko oluthile emanzini, lunyibilika lula kwi-methanol kunye ne-isopropanol, kwaye kunzima ukuyinyibilika kwi-chloroform kunye ne-ether. |
umsebenzi wamehlo | +27.0 degrees (C=1, amanzi). |
Imbonakalo | umgubo omhlophe wekristale |
I-Phenformin isetyenziswa kakhulu ukunyanga isifo seswekile esingaxhomekekanga kwi-insulin yabantu abadala kunye nesifo seswekile esixhomekeke kwi-insulin.Umsebenzi kukukhuthaza ukunyuswa kunye ne-glycolysis ye-glucose ngamaseli emisipha, ukunciphisa ukuveliswa kwe-glucose ngesibindi, kwaye ube nefuthe elichasayo le-hyperglycemic.Ingasetyenziswa ngokudibeneyo ne-insulin, eyenza kube lula ukulawula iswekile yegazi kunye nokunciphisa umthamo we-insulin.Kwisifo seswekile esityebileyo, ingasetyenziselwa ukuthintela ukutya kunye nokufunxa i-glucose emathunjini ukunciphisa ubunzima.
I-Phenformin isetyenziswa kakhulu ukunyanga isifo seswekile esingaxhomekekanga kwi-insulin yabantu abadala kunye nesifo seswekile esixhomekeke kwi-insulin.Umsebenzi kukukhuthaza ukunyuswa kunye ne-glycolysis ye-glucose ngamaseli emisipha, ukunciphisa ukuveliswa kwe-glucose ngesibindi, kwaye ube nefuthe elichasayo le-hyperglycemic.Ingasetyenziswa ngokudibeneyo ne-insulin, eyenza kube lula ukulawula iswekile yegazi kunye nokunciphisa umthamo we-insulin.Kwisifo seswekile esityebileyo, ingasetyenziselwa ukuthintela ukutya kunye nokufunxa i-glucose emathunjini ukunciphisa ubunzima.
Ukulawulwa komlomo: Idosi esetyenziswa ngokuqhelekileyo yi-50-200mg ngosuku, ithathwe kwiidosi ezintathu.Ekuqaleni, thatha i-25mg kanye, amaxesha angama-2-3 ngosuku, ngaphambi kokutya.Inokunyuka ngokuthe ngcembe ukuya kwi-50-100mg ngosuku.Ngokuqhelekileyo, iswekile yegazi iyancipha emva kweveki enye yonyango, kodwa ukuze ufikelele kumanqanaba aqhelekileyo eswekile yegazi, amayeza kufuneka aqhubeke kwiiveki ezi-3-4.