Inombolo yeCas: 1115-70-4 Ifomula yeMolekyuli: C4H11N5
| Indawo yokunyibilika | 233-236℃ |
| Ukuxinana | 1.48 g/cm³ |
| ixesha lokugcina | 15-30℃ |
| ukunyibilika | Inyibilika emanzini, inyibilika kwi-ethanol, kwaye ayinyibiliki kwiklorofomu nakwibenzene. |
| umsebenzi wamehlo | +25.7 degrees (C=1, amanzi) |
| Imbonakalo | umgubo omhlophe wekristale |
Indlela ye-pharmacological ye-molecular ayikaqondwa ngokupheleleyo.Kuyaziwa ukuba isebenza ubuncinane kwisibindi, ukunciphisa i-gluconeogenesis (okt ukuveliswa kwe-glucose) kunye nokunciphisa ukuxhathisa kwe-insulin.Olunye uphando lubonise ukuba lungenza i-AMP isebenze iprotein kinase (AMPK), enye yeendlela eziyimfuneko zokuthintela i-gluconeogenesis yesibindi kunye nokuphucula uvakalelo lwe-insulin kwindlela yokudluliselwa kwesignali ye-insulin.I-AMPK, njengeprotheyini kinase, idlala indima ebalulekileyo kungekhona kuphela kwindlela yokubonisa i-insulin, kodwa kunye nokulinganisela kwamandla kunye ne-glucose kunye ne-fat metabolism.Uvavanyo lwezilwanyana kunye nophononongo lweklinikhi lubonise ukuba lunokubangela utshintsho olubalulekileyo ekubunjweni kwe-fecal microbiota kwisifo seswekile, esinokuthi singafaki nje igalelo kwimfihlo kunye nesiphumo seglucagon njenge-peptide-1 (GLP-1), kodwa ikwangqina ukuphucula ubuntununtunu be-insulin. , ekwayenye yeendlela ezibalulekileyo zohlobo lwayo lwe-2 yesifo seswekile.
Le mveliso kufuneka isetyenziswe kwiidosi ezincinci kwaye yanda ngokuthe ngcembe ngokwemeko yesigulane.I-dose yokuqala yale mveliso (i-hydrochloride tablets) idla ngokuba yi-0.5 grams, kabini ngosuku;Okanye i-0.85 grams, kanye ngosuku;Thatha kunye nokutya.
Le mveliso kufuneka isetyenziswe kwiidosi ezincinci kwaye yanda ngokuthe ngcembe ngokwemeko yesigulane.I-dose yokuqala yale mveliso (i-hydrochloride tablets) idla ngokuba yi-0.5 grams, kabini ngosuku;Okanye i-0.85 grams, kanye ngosuku;Thatha kunye nokutya.
