Inombolo ye-Oxytetracycline Cas: 2058-46-0 Ifomula yeMolekyuli: C22H24N2O9•HCl
Indawo yokunyibilika | 180 ° |
Ukuxinana | 1.0200 (uqikelelo olurhabaxa) |
ixesha lokugcina | Umoya ongaphakathi, Ubushushu beGumbi 0-6°C |
ukunyibilika | >100 g/L |
umsebenzi wamehlo | N / A |
Imbonakalo | Umgubo oMthubi |
Ubunyulu | ≥97% |
I-Oxytetracycline yi-analog ye-tetracycline ebekwe yodwa kwi-actinomycete i-Streptomyces rimosus.I-Oxytetracycline sisibulali-zintsholongwane esiboniswa kunyango losulelo olubangelwa yiGram positive kunye neGram negative microorganisms ezifana neMycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, kunye neDiplococcus pneumoniae.Isetyenziswe kwizifundo kwi-oxytetracycline-resistance gene (otrA).I-Oxytetracycline hydrochloride isetyenziselwa ukufunda i-phagosome-lysosome (PL) fusion kwiiseli ze-P388D1 kunye ne-antibiotic susceptibility of Mycoplasma bovis isolates.
I-Oxytetracycline hydrochloride yityuwa elungiselelwe kwi-oxytetracycline ithatha inzuzo yeqela elisisiseko le-dimethylamino elikhupha ngokukhawuleza ukwenza ityuwa kwi-hydrochloric acid solutions.I-hydrochloride yindlela ekhethwayo yokwenziwa kwezicelo zamachiza.Njengazo zonke i-tetracyclines, i-oxytetracycline ibonisa i-antibacterial spectrum ebanzi kunye nomsebenzi we-antiprotozoan kwaye yenza ngokuzibophelela kwi-30S kunye ne-50S ye-ribosomal sub-units, ukuvimba iprotheni synthesis.